What Is Argireline™? – Topical Botox Alternative

argepicThe popular skin care ingredient Argireline™ is often referred to as the Topical Botox. For those who find Botox injections too expensive or simply don’t like needles, skin care products containing the peptide Argireline is an effective alternate receiving high praise by many.

One of the first places aging shows up is on the face… Fine lines start to form around the eyes and mouth that gradually deepen, becoming more noticeable. At first these lines are noticeable only with facial movement. At this stage, the lines are referred to as “dynamic” wrinkles, meaning they’re visible only with facial movements like smiling, frowning, etc.. Eventually, dynamic wrinkles become static wrinkles that are noticeable even without facial movement.

One way to treat dynamic wrinkles and keep them from becoming static lines is the use of an agent that relaxes the underlying muscles. This is usually with injections of botulinum toxin or Botox. Although Botox is effective for treating dynamic wrinkles, some people are wary of treatments that involve needles. Until recently, there wasn’t an alternative to Botox injections for relaxing the muscle. But now there’s a topical ingredient called acetyl hexapeptide-3, trademarked under the name Argireline.

Argireline is a patented peptide complex that is an ingredient currently used by many beauty product manufacturers. Argireline, which goes under the scientific name of Acetyl Hexapeptide-3, is manufactured by Lipotec. Lipotec is a Barcelona-Spain based cosmetics research lab and a well-known worldwide expert in advanced active ingredients for skin. The first peptide to reduce expressions lines.
An effective topical alternative to injections, with the added bonus of being much easier on the pocketbook.

Chemically speaking, Argireline is a peptide. The chemical compound is assembled in laboratories, which makes it a synthetic beauty ingredient. The peptide itself is a fragment of SNAP-25. You’ve probably never heard of SNAP-25, but you have heard of Botox: SNAP-25 is a substrate of Botulinum toxin, better known as Botox. Basically, Argireline promises to be a topical chemical compound that can be rubbed into your skin to give you Botox-like results without injections.

What is Argireline?   

The peptide is derived from natural proteins, and claims to actually relax facial muscles. By applying Argireline consistently over a period of time, you can dramatically reduce the formation of wrinkles on your face – especially in problem spots like your forehead and around your eyes.

So how exactly does Argireline “freeze” your skin in place? The secret to Argireline lies in its peptides. Peptides are just chains of amino acids. When these amino acids enter your skin cells, it inhibits the responses of your facial muscles, which means they contract with less force.
This goes well with the company’s “like Botox without the hassle” claims. The theory guiding both products is that relaxed facial muscles will minimize current wrinkles caused by repetitive muscle contractions, as well as prevent new wrinkles.

Even though products containing Argireline is less expensive than Botox, most still features higher prices than other anti-wrinkle products. As far as Botox is concerned, the injections can focus only on a specific area. But when it comes to Argireline, the majority of individuals can spread the cream all over their face.

In vivo study, Topical Argireline 10% is applied on lateral preorbital area twice daily for 30 days. The result demonstrates a significant anti-wrinkle activity by decreased skin wrinkle 30%. These findings demonstrate a significant anti-wrinkle activity for Argireline, in agreement with its in vitro and cellular activities. Topical Argireline represents a bio-safe alternative to BoNTs in anti-wrinkle therapy.
(source; ClinicalTrials.org – A service of the U.S. National Institutes of Health)
After 28 days of use the testing groups average wrinkle structure changed drastically. The average change in wrinkle depth for this study was 32%. 
When looking for skin care containing Argireline, be sure the product includes high percentage of Argireline. Products containing an effective level will have Acetyl Hexapeptide 3 listed at the top of the ingredient list.

Botox Versus Argireline

Argireline is basically a weaker version of Botox. The two serums are derived from the same ingredients and target the same processes within your skin.

The main difference between the effectiveness of Botox and the effectiveness of Argireline is that Argireline penetrates into your skin at a shallower level. Obviously, Botox relies on injections which can penetrate deep into the lower layers of your skin, while Argireline relies on topical applications.

That means Argireline will inevitably be less effective than Botox, and consistent use is important – but that’s true when comparing most injection products versus topical products.



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